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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Inverted day-night feeding during pregnancy affects the brain health of both maternal and fetal brains through increasing inflammation levels associated with dysbiosis of the gut microbiome in rats

Fig. 5

Active-phase fasting increased the level of LPS, which was associated with gut microbiota. a LPS levels in the cecum of pregnant rats. b LPS levels in serum. c LPS levels in the hippocampus. d–r Correlation between differential cecal genera and LPS levels, analyzed by Spearman correlation: d Akkermansia, e Ruminococcus torques group, f Romboutsia, g unclassified_f__Lachnospiraceae, h Dubosiella, i Bilophila, j Ruminococcus gauvreauii group, k norank_f__Oscillospiraceae, l NK4A214 group, m norank_f__Muribaculaceae, n Turicibacter, o unclassified_f__Peptostreptococcaceae, p Christensenella, q Candidatus Stoquefichus, r Relative expression of hippocampal TLR 4 mRNA. The results in panels a–c and r were presented as mean ± SEM, with ND group n = 8 and IF group n = 7. Panels d–r represented ND group = 7 and IF group n = 6. *p < 0.05, **p < 0.01, ***p < 0.001

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Journal of Neuroinflammation

ISSN: 1742-2094