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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Dynamic phosphorylation of Fascin-1 orchestrates microglial phagocytosis and neurological recovery after spinal cord injury

Fig. 9

The function of the balance of Fascin-1 phosphorylation in modulating microglial phagocytosis following SCI. Microglia has extremely robust phagocytic activity in early injury stage (3 dpi), but appears phagocytosis blockage in subacute stage (7 dpi). Pharmacological intervention targeting the Mas1/PKCγ axis with captopril effectively restores the balance of Fascin-1 phosphorylation and microglial phagocytosis

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Journal of Neuroinflammation

ISSN: 1742-2094