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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: A molecular brain atlas reveals cellular shifts during the repair phase of stroke

Fig. 5

Comparative gene expression profiles in mouse and human post-stroke. (A) Schematic of human and mouse stroke (B) Scatter plot displaying the Person correlation for gene expression changes between mouse and human post-stroke. (C) Heatmap of common upregulated genes in human and mouse stroke (upper) and differentially expressed genes in human and mouse stroke (lower) (D) Stacked barplot of common and unique upregulated genes in the top 2000, 500 and 100 gene sets from both mouse and human datasets (upper) and Venn diagram of shared and unique genes with a fold change > 2. (E-G) Overrepresentation analysis of top 2000 genes present in (E) both mouse and human datasets, (F) genes exclusively identified in mouse stroke dataset (G) and genes only present in human stroke dataset. All p-values ***,< 0.001

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