Fig. 3
From: Gut microbiota and their influence in brain cancer milieu
Impact of the therapeutic regimen administration on gut microbiota and microbial metabolites in brain cancer therapy: Administration of temozolomide, bevacizumab, high glucose diet, probiotics such as Bifidobacterium lactis, Bifidobacterium breve, Bifidobacterium longum, Bifidobacterium bifidum and Lactobacillus plantarum changes the dysbiosis in the gut microbial composition. The microbial metabolites produced by the gut microbiota pass through the lymphatic, circulatory system, etc., reaching and crossing the blood-brain barrier and modulating the components in the microenvironment, ultimately regulating the progression of brain cancer. ↑ - increase, ↓ - decrease in the abundance. This figure was created with BioRender.com