Fig. 7

Eed loss alleviates periphery inflammation in EAE mice. A–E Representative images (A) and bar graph (B–E) for flow cytometry analysis of the percentages and numbers of Th1 (CD4⁺IFN-γ⁺), Th17 (CD4⁺IL-17⁺), Th2 (CD4⁺IL-4⁺) and Treg (CD4⁺Foxp3⁺) in the draining lymph nodes from WT and Eed cKO EAE mice at dpi 23. n = 3. F–H Representative images (F) and bar graph (G, H) for flow cytometry analysis of the percentages and numbers of total DCs (CD11c⁺) and mature DCs (CD11c⁺CD80⁺) in the spleen from WT and Eed cKO EAE mice at dpi 23. n = 3. I Bar graph for flow cytometry analysis of the percentage of CD80⁺ in CD11c⁺ DCs in the spleen from WT and Eed cKO EAE mice at dpi 23. n = 3. Data are presented as mean ± SD. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ns, not significant