Fig. 4

Moss-derived recombinant human CFH variants CPV-101 and CPV-104 attenuate light-induced retinal degeneration. A Representative heat maps from fundus images at indicated time points from control and light-exposed mice. Lower panel shows OCT scan. Scale bar: 200 µm. ONL, outer nuclear layer. B Quantification of retinal thickness in the central (circle diameter 3 mm) and peripheral area (circle diameter 6 mm). Data show mean ± SEM; n = 18–27 eyes. One-way ANOVA followed by Sidak’s multiple comparison test; *P ≤ 0.05, **P ≤ 0.01 and ***P ≤ 0.001