Fig. 2
From: Akkermansia mono-colonization modulates microglia and astrocytes in a strain specific manner
Mono-colonization with Akkermansia alters microglia gene expression. Altered gene expression in AmT mono-colonized animal microglia compared to Veh (A) and representative DEGene count graphs (B). Genes altered between Am-H3 vs. Veh (C) and representative bar graphs of DEGene counts (D). Significantly altered genes between Bc and Am-H3 (E) and representative graphs of up and downregulated DEGene counts (F). Ingenuity Pathway Analysis (IPA) top pathways altered in animals mono-colonized with microbes vs. vehicle treated for relevant pathway families (G). Pathways identified in IPA significantly (-log(p-val) > 1.3) for AmT vs. Am-H3 groups (H). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. n = 6 Veh, Am-H3, n = 7 for AmT and Bc