Fig. 7

RNA-seq analysis at PNd4 defines altered cochlear environment in MCMV-infected mice at PNd4. RNA was isolated from cochlea o PNd4 mice and RNA-seq performed as described in the methods. (A) GSEA analysis was performed to determine pathways most heavily enriched in MCMV-infected mice. Select pathways with their respective pathway gene set size and q value are shown in this panel. (B) Representative heatmaps of pathways related to response to virus and tissue remodeling at PNd4 illustrate the clear difference in gene expression between cochleae from uninfected controls and MCMV-infected mice