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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Asrij/OCIAD1 depletion reduces inflammatory microglial activation and ameliorates Aβ pathology in an Alzheimer’s disease mouse model

Fig. 6

Graphical summary of the role of Asrij in microglial inflammatory activation and AD pathophysiology. Asrij promotes activation of inflammatory signalling pathways in AD microglia and thus exacerbates neuroinflammation and AD pathology. Hence, Asrij depletion curtails microglial activation and associated neuropathology to ameliorate cognitive dysfunction in AD

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Journal of Neuroinflammation

ISSN: 1742-2094