Fig. 1
From: MAIT cell deficiency exacerbates neuroinflammation in P301S human tau transgenic mice
MAIT cells are present in meninges of P301S mice and retain expression of antioxidant molecules. A Representative flow cytometry profiles of MAIT cells in the meninges of 7-month-old P301S mice and control wildtype mice. Plots were pre-gated on CD45+CD11b−B220−Thy1+ cells. B Numbers of MAIT cells in the meninges, hippocampus (HP), and cortex of 7-month-old P301S mice and wildtype mice. C Representative flow cytometry profiles of MAIT cells in the hippocampus and cortex. D Representative flow cytometry profiles showing expression of the indicated proteins by meningeal MAIT cells in P301S mice. Plots were pre-gated on meningeal MAIT cells in P301S mice. E mRNA levels of the indicated genes in meningeal MAIT cells of 7-month-old P301S mice and control wildtype mice. Data are from 6 mice per group pooled from 2 independent experiments B, or 4 independent experiments with 5 mice per group pooled per experiment E. Data were normalized to Gapdh. Error bars = mean ± SEM. **p < 0.01. Sex information in Additional file 1