Fig. 1

ErbB4 small molecule agonist ameliorates cognitive behavioral impairments in mice exposed to PS-MPs. (A) Representative traces in open field experiment. (B) The statistical analysis related to open field test. (C) Representative heat map in Y maze exploration experiment, with arm A denoting the initial arm. (D) The rate of spontaneous alternation in Y maze experiment. (E) Representative traces from the new object recognition (NOR) experiment. (F) Statistical analysis related to the NOR experiment. (G) Representative swimming traces from the Morris water maze (MWM) exploration experiment. (H) The statistical analysis of MWM exploration test. Statistical analysis was conducted using one-way analysis of variance (ANOVA) followed by Tukey’s post hoc test for multiple comparisons, and the data are presented as means ± standard error of the mean (SEM). Statistical significance is indicated by *p < 0.05, **p < 0.01, and ***p < 0.001, with n = 8 per group