Fig. 3
Structural analyses show cell-type specific neuronal vulnerability during EAE. A Representation of the most prominent layers in the main olfactory bulb. Glomerular layer = GL, external plexiform layer = EPL, mitral cell layer = MCL, internal plexiform layer = IPL, granular cell layer = GCL. B–G Representative immunofluorescence images and quantitative measurement of different cell populations according to their main cell markers measured in the olfactory bulb per mm2 in healthy and EAE mice (n = 5–8 per group): B Tyrosine hydroxylase (TH), C Calbindin, D Calretinin, E Parvalbumin (PV), F NeuN and G Doublecortin (DCX). The analyzed layers are described and colored according to the representative image in A. Scale bars = 100 µm. Bars show mean values ± s.e.m. Statistical analysis was performed by unpaired, two-tailed Student's t-test; *P < 0.05