Fig. 4

Systemic IL-6 and IL-6R levels increased at 24 h in mice after stroke. (A) Plasma IL-6 levels in mice sham and 24 h after MCAO. (B) Plasma levels in males. (C) Females. (D) sIL-6R levels. Data presented as mean ± SEM. n = 6–9/gp. Two group comparisons were analyzed by Unpaired t-test with Welch’s correction and by Ordinary one-way ANOVA with Tukey’s multiple comparisons test. *p < 0.05; **p < 0.01