Fig. 6
From: CD22 modulation alleviates amyloid β-induced neuroinflammation
Working model presenting suciraslimab’s mechanism of action. Anti-inflammatory model: Suciraslimab targets microglia, suppresses Aβ-induced inflammation and reduces the release of CX3CL1, CCL24 and CCL4. Through reducing neuroinflammation, suciraslimab improves memory and cognitive functions in hCD22 transgenic mice