Fig. 1

Cells of the blood brain barrier (BBB). (A) The principal cells of the BBB are cerebral endothelial cells (CEC) which form the capillaries of the central nervous system. Pericytes embedded in the basement membrane and astrocytes which send endfeet are additional components of the BBB. (B) Astrocytes also interact with neurons and microglia and mediate endothelial cell-neuron and endothelial cell-microglia communication. Created with BioRender.com