Skip to main content

Table 3 Associations among inflammation scores, white-matter lesions, and striatal D2-receptor availability

From: Associations between inflammation and striatal dopamine D2-receptor availability in aging

 

Variable

β

t

p

Whole sample

Model 1:

F (5, 156) = 2.79

p = 0.02*

R2 = 0.08

Adjusted R2 = 0.05

Model 2:

F (5, 159) = 2.94

p = 0.01*

R2 = 0.08

Adjusted R2 = 0.06

Inflammation score 1

White-matter lesions

NK

Granulocytes

Age

Inflammation score 2

White-matter lesions

NK

Granulocytes

Age

−0.15

−0.2

0.03

−0.15

0.03

−0.17

−0.21

0.07

−0.11

0.03

−1.86

−2.66

0.35

−1.6

0.33

−1.88

−2.75

0.75

−1.33

0.33

0.07

< 0.01

0.72

0.11

0.74

0.06

< 0.01

0.45

0.19

0.74

Men

Model 3:

F (5, 83) = 3.32

p = 0.00**

R2 = 0.17

Adjusted R2 = 0.12

Model 4:

F (5,85) = 2.87

p = 0.02*

R2 = 0.14

Adjusted R2 = 0.09

Inflammation score 1

White-matter lesions

NK

Granulocytes

Age

Inflammation score 2

White-matter lesions

NK

Granulocytes

Age

−0.33

−0.20

−0.01

−0.21

−0.07

−0.34

−0.21

0.11

−0.11

−0.06

−3.18

−2.07

−0.07

−1.66

−0.73

−2.95

−2.19

0.85

−0.83

−0.64

< 0.01

0.04

0.94

0.10

0.47

< 0.01

0.03

0.4

0.37

0.52

Women

Model 5:

F (5, 67) = 1.49

p = 0.21

R2 = 0.10

Adjusted R2 = 0.03

Model 6:

F (5, 68) = 1.63

p = 0.16

R2 = 0.11

Adjusted R2 = 0.04

Inflammation score 1

White-matter lesions

NK

Granulocytes

Age

Inflammation score 2

White-matter lesions

NK

Granulocytes

Age

0.09

−0.18

0.16

0.00

0.13

0.06

−0.20

0.13

−0.07

0.15

0.71

−1.48

1.22

0.00

1.10

0.43

−1.68

0.91

−0.51

1.26

0.48

0.14

0.23

1.00

0.28

0.67

0.10

0.37

0.61

0.21

  1. Regression models were conducted for the whole sample (models 1, 2), and in men (models 3, 4) and women (models 5, 6) separately. Striatal D2-receptor availability represents an average for putamen and caudate. Covariates in all models are age and NK and granulocyte count
  2. Values in bold survived Bonferroni adjustment (p = 0.05/5)