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Table 1 Characteristics of new onset-MG patients and controls

From: Targeting NF-kappaB-inducing kinase shapes B-cell homeostasis in myasthenia gravis

Characteristics

PBMC for FCM detection

Serum for ELISA detection

Controls (n = 32)

New-onset MG(n = 45)

P

Controls (n = 50)

New-onset MG(n = 76)

P

Age, years

57.5(51.00,63.75)

63(48.50,72.00)

0.227

53.00(46.50, 57.25)

55.00(41.25, 65.00)

0.419

Sex, n(%)

  

0.363

  

0.207

 Female

19(59.38)

22(48.89)

 

32(64.00)

40(52.63)

 

 Male

13(40.63)

23(51.11)

 

18(36.00)

36(47.37)

 

Age of onset, n(%)

      

 EOMG (age < 50 y)

 

15(33.33)

  

30(39.47)

 

 LOMG (age ≥ 50 y)

 

30(66.67)

  

46(60.53)

 

Type, n(%)

      

 OMG

 

20(44.44)

  

26(34.21)

 

 GMG

 

25(55.56)

  

50(65.79)

 

MGFA at admission, n(%)

      

 I

 

20(44.44)

  

26(34.21)

 

 II

 

10(22.22)

  

17(22.37)

 

 III

 

11(24.44)

  

20(26.32)

 

 IV

 

4(8.89)

  

13(17.11)

 

Thymoma, n(%)

      

 Without

 

34(75.56)

  

52(68.42)

 

 With

 

11(24.44)

  

24(31.58)

 

AchR-Ab, n(%)

      

 Positive, n(%)

 

45(100.00)

  

76(100.00)

 

 Negative, n(%)

 

0(0.00)

    
  1. Flow cytometry (FCM), Enzyme-linked immunosorbent assay (ELISA), Early-onset myasthenia gravis (EOMG), late-onset myasthenia gravis (LOMG), ocular myasthenia gravis(OMG), generalized myasthenia gravis(GMG), Foundation of America Clinical Classification(MGFA), Acetylcholine receptor antibody (AchR-Ab)