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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Cross-species comparisons between pigs and mice reveal conserved sex-specific intraspinal inflammatory responses after spinal cord injury

Fig. 1

Sex has no effect on locomotor recovery and tissue sparing after SCI in pigs. (A) Behavioral recovery on the Porcine Thoracic Injury Behavioral Scale (PTIBS) during the 6 weeks of survival post-SCI. Thoracic contusion SCI resulted in sustained hindlimb dysfunction relative to shams. Locomotor functional significantly improved over time (p = 0.02 main effect of time for SCI groups) with no significant differences between males and females. (B) There was little spared tissue at the lesion epicenter 6-weeks after injury. (C) EC stained (blue = myelin) sections representative of lesion pathology 6-weeks after SCI show very little spared tissue with no significant effects between males and females. (n = 8–14) Mean ± SEM

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Journal of Neuroinflammation

ISSN: 1742-2094