Fig. 7

MRI shows that difluorosamine alleviates brain tissue loss over 14 days of ICH. A A 3D representative of segmented perihematomal area and lesion core. B, C Representative segmented lesion core (B) and perihematomal area (blue) (C) of FLASH sequences at day 14 after ICH. Scale bar = 3 mm. D–G Representative images of fractional anisotropy (D), mean diffusivity (E), axial diffusivity (F) and radial diffusivity (G) from mice at day 14 after injury. Scale bar = 3 mm. H–K Bar graphs comparing data from DTI of the perihematomal area between control and DIF mice: fractional anisotropy (H), mean diffusivity (I), axial diffusivity (J) and radial diffusivity (K). N = 7 in control group and n = 6 in DIF group. Data are presented as the mean ± SEM. Unpaired two-tailed Student’s t-test; ns: not significant. Significance indicated as *p < 0.05