Fig. 4
Injection with anti-IL-17 prevents the alterations in the GABAergic neurotransmission in cerebellum of hyperammonemic rats at 4 days of hyperammonemia. Membrane expression of (A) GABAAα2, (B) GABAAβ3, (C) GABAAγ2, (D) KCC2, and (E) NKCC1 were analyzed using BS3 cross-linker. Representative images of the blots for each protein are shown. Values are expressed as percentage of controls and are the mean ± SEM of 7 rats/group. One-way ANOVA followed by Fisher’s LSD post-hoc test was performed to compare all groups. Values significantly different from controls are indicated by asterisk (*p < 0.05, **p < 0.01) and values significantly different from HA group are indicated by a (a = p < 0.05, aa = p < 0.01, aaa = p < 0.001, aaaa = p < 0.0001)