Fig. 8

Conditional knockout of adrb2 in microglia partly reduced insoluble Aβ40 in female 5XFAD mice. Bar graphs depict thalamic concentrations of soluble and insoluble (A, B) Aβ40 and (C, D) Aβ42. *p < 0.05, ** p < 0.01, ***p < 0.001, ****p < 0.0001; Sidak’s post-hoc comparison of means following two-way ANOVA (adrb2 cKO x sex)