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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer’s disease

Fig. 10

Effect of conditional knockout of adrb2 in microglia in female 5XFAD and non-carrier mice. Log2-fold change graphs depict the effects of (A) 5XFAD (5XFAD/non-carrier; n = 21) and (B) adrb2 cKO in microglia (5XFAD-cKO/5XFAD-control; n = 11) in female mice on a panel of inflammation-related markers. (C) Bar graphs show raw data from proteins affected by adrb2 cKO, as indicated in panel B. For (A) * indicates the main effect of 5XFAD. For (B) and (C) * indicates post-hoc Sidak’s comparison of means following two-way ANOVA (5XFAD x adrb2 cKO). *p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001

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Journal of Neuroinflammation

ISSN: 1742-2094