Table 1 Characteristics of patient samples included in RNA-Sequencing analysis
Preliminary analysis | |||||||||||||
Sample # | Age | Sex | DM Type | Ocular Diagnosis | VH | TRD | Relevant systemic disorders | Lens status | PVD | Previous anti-VEGF treatment | Previous PRP treatment | Cell count | RNA concentration (pg/µl) |
+/- lysis | +/- lysis | ||||||||||||
1 | 83 | F | NA | MP | NA | NA | asthma | phakic | no | NA | NA | 90/264 | 71/116 |
68 | M | II | MP | NA | NA | - | phakic | no | NA | NA | |||
69 | F | NA | MP | NA | NA | - | phakic | no | NA | NA | |||
2 | 79 | F | NA | MP | NA | NA | - | phakic | yes | NA | NA | 94/86 | 104/154 |
68 | F | NA | MP | NA | NA | - | phakic | no | NA | NA | |||
76 | F | NA | MP | NA | NA | asthma, st. p. fibromyalgia, st. p. borreliosis | phakic | no | NA | NA | |||
78 | F | NA | MP | NA | NA | - | phakic | no | NA | NA | |||
3 | 61 | F | NA | MH | NA | NA | - | phakic | no | NA | NA | 79/139 | 84/11 |
74 | F | NA | MP | NA | NA | st. p. chemotherapy for breast carcinoma, Parkinson’s | phakic | no | NA | NA | |||
82 | M | NA | MP | NA | NA | - | phakic | no | NA | NA | |||
4 | 81 | F | NA | MP | NA | NA | rheumatoid arthritis | pseudophakic | yes | NA | NA | 139/147 | 43/85 |
67 | F | NA | MP | NA | NA | - | phakic | no | NA | NA | |||
76 | F | NA | MH | NA | NA | - | phakic | no | NA | NA | |||
Main analysis | |||||||||||||
Sample # | Age | Sex | DM Type | Ocular Diagnosis | VH | TRD | Relevant systemic disorders | Lens status | PVD | Previous anti-VEGF treatment | Previous PRP treatment | Cell count | RNA concentration (pg/µl) |
5 | 77 | M | II | PDR | + | + | - | phakic | no | no | yes | 280 | 38 |
6 | 40 | M | I | PDR | + | + | - | phakic | no | no | yes | 2300 | 322 |
7 | 56 | M | II | PDR | + | + | - | phakic | no | no | no | 980 | 49 |
8 | 29 | F | I | PDR | + | + | - | phakic | no | no | no | 1800 | 82 |
9 | 66 | F | II | PDR | + | - | - | pseudophakic | yes | > 3 months | yes | 454 | 68 |
10 | 62 | M | I | PDR | - | + | st. p. kidney and pancreas transplantation | pseudophakic | no | no | yes | 723 | 64 |
11 | 63 | M | II | PDR | + | + | renal insufficiency | phakic | no | no | no | 1077 | 211 |
12 | 64 | F | II | PDR | + | - | - | pseudophakic | no | no | yes | 512 | 86 |
13* | 79 | F | II | MP | NA | NA | asthma | pseudophakic | no | NA | NA | 944 | 109 |
14 | 72 | M | NA | MP | NA | NA | - | pseudophakic | yes | NA | NA | 291 | 142 |
15 | 73 | M | NA | MP | NA | NA | - | pseudophakic | no | NA | NA | 464 | 161 |
16 | 73 | F | NA | MP | NA | NA | fibromyalgia | pseudophakic | no | NA | NA | 701 | 73 |
17* | 68 | M | NA | MH | NA | NA | psoriasis | phakic | no | NA | NA | 424 | 73 |
18 | 88 | M | NA | MH | NA | NA | - | pseudophakic | no | NA | NA | 315 | 301 |
19 | 78 | F | NA | MH | NA | NA | st. p. giant cell arteritis, celiac disease | phakic | yes | NA | NA | 550 | 110 |
20 | 69 | M | NA | MH | NA | NA | - | phakic | no | NA | NA | 164 | 174 |
21 | 72 | F | NA | MH | NA | NA | - | pseudophakic | no | NA | NA | 240 | 78 |