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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy

Fig. 5

Erythrophagocytosis in hyalocytes. (A) Boxplots of the expression of marker genes of erythrophagocytosis and iron regulator genes in proliferative diabetic retinopathy (PDR, red) and control (green) hyalocytes. *p < 0.05. (B) Immunohistochemical staining of cultured porcine hyalocytes for ionized calcium-binding adaptor molecule 1 (IBA-1), cluster of differentiation 235a (CD235a) and Phalloidin. Nuclei are counterstained with 4′,6-Diamidin-2-phenylindol (DAPI). Within the cytoplasm of hyalocytes, vesicles containing CD235a- (= erythrocyte debris), but also DAPI-stained particles (= digested nuclei) were observed. Scale bar corresponds to 50 μm

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Journal of Neuroinflammation

ISSN: 1742-2094