Fig. 2

Adaptive optics scanning light ophthalmoscopy (AOSLO) imaging of macrophage-like cells in the vitreoretinal interface. Two adjacent hyalocytes with different movement behaviors over 30 min of AOSLO imaging in (top row, A1-A4; modified from [18]) a 32-year-old healthy control and (bottom row, B1-B4) a 26-year-old proliferative diabetic retinopathy (PDR) patient. A5 & B5. Chromo-temporal map composites of the four time points over 30 min, which indicate movement of cell bodies and processes across the imaging period. Time of acquisition in the lower-left corner is displayed in mins:secs. A video of the entire imaging region of interest, which includes these four cells, is shown in Additional File 1