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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Shifts in the spatiotemporal profile of inflammatory phenotypes of innate immune cells in the rat brain following acute intoxication with the organophosphate diisopropylfluorophosphate

Fig. 4

a Representative photomicrographs of piriform cortex-amygdala immunostained for IBA1 (red) to identify microglia and iNOS (green) to identify pro-inflammatory cells, then counterstained with DAPI (blue) to identify cell nuclei. Solid boxes identify the field in the lower magnification image that is shown at higher magnification. b, c (GMR) (dot) of the mean density of iNOS+ IBA1+ cells in various brain regions of animals intoxicated with DFP relative to Veh at 1, 3, 7, 14, and 28 DPE with 95% CI (bars) in males (b) and females (c). The y-axis is shown as a log-scale. CI that does not include 1 (the gray horizontal line) and is shaded blue indicates a significant difference in the density of iNOS+ IBA1+ nuclei between DFP and Veh after FDR correction

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Journal of Neuroinflammation

ISSN: 1742-2094