Fig. 2

Immunoinfiltration analysis and WGCNA revealed the role of immune cells in IA. A Immunoinfiltration landscape in the GSE75436 dataset. B Percentage of immune cells in IA. C Abundance levels of various immune cells in the IA and control groups. D Immune scores, stromal scores, and microenvironment scores derived from the xCell algorithm. E Selection of the optimal soft-thresholding power (β). F Identification of 10 modules presented as a clustering tree. G Correlations between modules and immune cells. H The correlation between the light green module and Mast_cells_resting, and the correlation between the pink module and M2 macrophages. I Extraction of 538 hub genes from the light green and pink modules intersecting with DEORGs, resulting in 16 key genes