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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: iPLA2β loss leads to age-related cognitive decline and neuroinflammation by disrupting neuronal mitophagy

Fig. 7

iPLA2β deficiency leads to alterations in mitochondrial phospholipid metabolism in aged PFC. A Heat map representing individual LPC species and lipidomic analysis of LPC species were significantly altered in the KO group in 24 M PFCs. B Heat map representing individual LPE species and lipidomic analysis of LPE species significantly altered in the KO group in 24 M PFCs. C Heat map representing individual PC species and lipidomic analysis of PC species significantly altered in the KO group in 24 M PFCs. D Heat map representing individual PE species and lipidomic analysis of PE species significantly altered in the KO group in 24 M PFCs

MUFA represents “monounsaturated fatty acid”; PUFA represents “polyunsaturated fatty acid”. Data are presented as the mean ± SEM; p values were obtained using two-sided unpaired Student’s t-tests (A, B, C, and D). * p < 0.05. **, p < 0.01; ***, p < 0.001

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