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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease

Fig. 6

Altered microglia morphology in Apoa1bp−/− APP/PS1 mouse brain. (A) Representative IBA1-positive microglia cells (green) and skeletonized rendering in the cortex of 6 months-old female mice. Scale bar, 20 μm. (B) Skeletonize macros in ImageJ were used to measure the number of branches, branch length, the number of cells per field of view, and the soma size (195–313 microglial cells per group). An average of two fields of view for each mouse (n = 5 per group). Mean ± SEM. One-way ANOVA with Tukey’s multiple comparisons test

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Journal of Neuroinflammation

ISSN: 1742-2094