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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Suppression of the JAK/STAT pathway inhibits neuroinflammation in the line 61-PFF mouse model of Parkinson’s disease

Fig. 4

scRNA-Seq Reveals an PFF-induced MM Inflammatory Cluster Which is Modulated by AZD1480 Treatment. (A) UMAP visualization of MM clusters from monomer, PFF + VH, or PFF + AZD1480 (25 mg/kg/day) bilaterally injected mice. (B) Cell numbers of the five MM clusters analyzed by scRNA-Seq. C. Dot plot of conserved marker genes in the five MM clusters across groups. D. Violin plots showing the expression-level distribution of MHC Class II genes across groups

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Journal of Neuroinflammation

ISSN: 1742-2094