Fig. 4
The magnitude and neuroinflammatory gene expression response to trauma are brain region dependent, and the mode of injury is independent. t-distributed stochastic neighbor embedding (tSNE) data visualization and analysis were used to plot the 2−ΔΔC(t) profiles of 74 genes for each regional brain biopsy sample, and the results demonstrated that the gene expression profiles of individual samples tended to cluster by region as opposed to timepoint or injury model. The dotted area around the clusters represents the circle of best fit at an 85% confidence interval for gene expression