Fig. 6

Tet1 intervention improved hippocampal cognitive dysfunction in IH mice. Measured in the Barnes maze: (A) Exploratory trajectories on days 5 and 12. (B) Latency to identify target box on days 5 and 12. (C) Latency to identify target box during the 4-day training period. Measured in the Y-maze: (D) Alternation behavior. (E) Number of arm entries. Measured in the NOR: (F) Discrimination index. (G) Total interaction time. Analysis was performed by Student’s t test. All data are presented as the mean ± standard deviation