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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Tet1-mediated 5hmC regulates hippocampal neuroinflammation via wnt signaling as a novel mechanism in obstructive sleep apnoea leads to cognitive deficit

Fig. 5

Tet1 knockdown was effective in vitro and in vivo. (A) The illustration of Tet1 intervention. (B) The design of the lentivirus carrying shTet1. (C) The expression of Tet1 in N2A cells using qPCR. (D) The expression of TET1 in the hippocampus using IHC staining and qPCR. (E) The subcellular localization of TET1 in the hippocampus using IF staining. Analysis was performed by Student’s t test. All data are presented as the mean ± standard deviation

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Journal of Neuroinflammation

ISSN: 1742-2094