Fig. 1

IH exposure induced the upregulation of TETs and total 5hmC in the hippocampus of mice. (A) The illustration of IH modeling. (B) Body weight and hippocampal PO2. (C) BOLD-fMRI analysis of the hippocampus. (D) Total amount of 5hmC in the hippocampus using standard DNA dot blot. (E) The expression of TET1, TET2, and TET3 in the hippocampus using IHC staining and qPCR. Analysis was performed by Student’s t test. All data are presented as the mean ± standard deviation