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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Proteomic profile of extracellular vesicles from plasma and CSF of multiple sclerosis patients reveals disease activity-associated EAAT2

Fig. 5

Comparison between CSF and plasma EV proteomes associated with MS relapses. A Shared EV proteins belonging to different cellular components. B Venn diagram showing ten common proteins, four of which involved in synaptic transmission. C Representative Western blot of SEC-purified EVs from plasma samples of relapsing RRMS patients and healthy controls for EAAT2 detection. Lanes 1 and 2: SEC-purified plasma EV samples of 2 healthy controls; Lane: M marker; Lanes 3 and 4: SEC-purified plasma EV samples of 2 relapsing RRMS patients. D Representative Western blot of SEC-EVs 20K and f SEC-EVs 100K from plasma samples of a relapsing RRMS patient and a healthy control for EAAT2 detection. Lanes 1 and 2: SEC-EVs 20K and SEC-EVs 100K respectively of a healthy control; Lane: M marker; Lanes 3 and 4: SEC-EVs 20K and f SEC-EVs 100K respectively of a relapsing RRMS patient

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Journal of Neuroinflammation

ISSN: 1742-2094