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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Traumatic brain injury alters the effects of class II invariant peptide (CLIP) antagonism on chronic meningeal CLIP + B cells, neuropathology, and neurobehavioral impairment in 5xFAD mice

Fig. 9

CAP treatment mitigates FPI-induced acute motor deficits in 5xFAD mice. Mouse gait was analyzed using the digigait 1 day post injury to assess motor deficits. 5xFAD FPI + Veh mice had significantly increased stance/swing (A) and a trending increase in paw angle (B) in the right hind leg, indicating an overall change in motor function after injury. These deficits were not apparent in the 5xFAD FPI + CAP mice. Data are represented as Mean ± SEM; n = 6 for vehicle groups, n = 12 for CAP groups; *p < 0.05

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Journal of Neuroinflammation

ISSN: 1742-2094