Fig. 6

The CD36-Traf5-MAPK axis influences microglial polarization post-TBI. (A, B) Immunofluorescence images of pro-inflammatory (A) and anti-inflammatory (B) microglia polarization in the corpus callosum following TBI in different experimental groups. (C, D) Quantification of Iba1⁺/iNOS⁺ double-positive cells (C) and Iba1⁺/Arg1⁺ double-positive cells (D). (E, F) mRNA expression levels of iNOS (E) and Arg1 (F) in the corpus callosum at 7 days post-TBI. (G–I) Western blot analysis and quantification of iNOS and ARG1 expression. Data represent mean ± SEM for 4 mice per group. *P < 0.05, **P < 0.01, ***P < 0.001