Fig. 5

Specific genera of bacteria are enriched in the high glycemic index and ketogenic diets. DNA was extracted from 26-week-old male mice and 16S ribosomal RNA gene amplicon sequencing performed. A The top 30 genera displayed as a relative abundance heatmap. B DESeq analysis of bacterial abundance between diets, where individual dots represent different amplicon sequence variants within the genus. N = 8–10 per group. Statistical comparisons of bacterial abundance were conducted using the DESeq package and involved pairwise Chi-Squared Tests, and results were filtered based on a significance threshold of Benjamini-Hochberg adjusted p-value < 0.01