Fig. 8

Transplantation of MSCs ameliorated EAU in vivo. (A) Representative fundus photographs of the eyes from EAU mice at 21 d.p.i., transplanted with MSC^tdTomato or MSC^CCR5 cells, or administered with PBS. (B) Representative fundus photographs (left) and OCT images (right) of the eyes from EAU mice at 21 d.p.i., transplanted with MSC^tdTomato or MSC^CCR5 cells, or administered with PBS. The arrows point to inflammatory infiltrating cells and the asterisks indicate retinal folds and detachment in EAU eyes. (C) Clinical grade scores of eyes in the PBS, MSC^tdTomato and MSC^CCR5 groups at 0, 14 and 21 d.p.i. Data are presented as mean ± SEM (n = 12–32 eyes per group). *p < 0.05, **p < 0.001, ***p < 0.0001