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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Interleukin-9 protects from microglia- and TNF-mediated synaptotoxicity in experimental multiple sclerosis

Fig. 7

Therapeutic treatment with IL-9 ameliorates EAE disease. (A) The graph shows representative clinical courses of EAE IL-9 and EAE VHL mice treated starting from the day of disease onset. IL-9 therapeutic treatment significantly ameliorated EAE disease progression. EAE VHL N = 8, EAE IL-9 N = 8; Mann-Whitney test from 19 to 28 dpi, *** p < 0.001). (B) MSNs from mice therapeutically treated with IL-9 (grey) showed reduced half width and decay time compared to EAE VHL (black) condition. EAE VHL n = 7, EAE IL-9 n = 18; Unpaired T-test *p < 0.05. **p < 0.01

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