Fig. 1
From: Therapeutic effects of orexin-A in sepsis-associated encephalopathy in mice
OXA ameliorates mood and cognitive deficits and hippocampal neuronal damage 1 day after sepsis in a dose-dependent manner. A Schematic timeline of the experimental procedures. B Time in the central zone and C distance of activity in the open field. D Resting time within 5 min in the tail suspension test. E Percentage of time spent exploring and F percentage of distance activity in the C-arm in the Y-maze. G Open field test and Y-maze movement trajectory maps. The above behavioral tests were performed 1 day after surgery. n = 8 per group. Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****P < 0.0001