Fig. 2
From: Taming microglia: the promise of engineered microglia in treating neurological diseases
Mechanisms of CAR–microglia/macrophages. A Gliomas-resident microglia/macrophages express GSC-specific CARs to eliminate GSC and prevent glioblastoma relapses. B UZPMs induce macrophages to express CTLA4 and melatonin to increase M2 anti-inflammatory microglia to alleviate inflammation-related depression. This figure was created with https://www.biorender.com