Topographic distribution of inflammation factors in a healing aneurysm

Table 1 Topography of humoral markers

	FGF	Il6	MMP2	MMP9	TNF-α	VEGF
(Unaffected) Adjacent vessel	1 [0.70–1.30]	1 [0.35–1.468]	1 [0.40–1.60]	1 [0.29–1.16]	1 [0.44–1.38]	1 [0.73–1.45]
Aneurysm neck	2 [0.99–1.91]	1 [0.84–1.71]	1 [0.73–1.45]	1 [0.41–1.22]	1 [0.58–1.43]	1 [0.78–1.59]
Aneurysm dome	1 [0.59–1.77]	1 [0.29–1.16]	1 [0.70–1.30]	1 [0.55–1.27]	1 [0.30–0.97]	1 [0.30–0.98]
Thrombus	1 [0.74–1.80]	2 [1.29–2.16]	2 [1.20–2.26]	1 [0.96–1.59]	2 [1.41–2.04]	1 [0.62–1.56]
Neointima	2 [0.99–2.07]	2 [1.44–2.38]	3 [2.30–2.98]	2 [2.00–2.00]	2 [1.41–2.04]	1 [0.73–1.45]
p-value (Kruskal–Wallis)	0.3	0.001	< 0.0001	< 0.0001	< 0.0001	0.2

Humoral inflammation factors were present in all ROIs, but more pronounced in the thrombus and in the neointima. The table shows median value and lower and upper 95%-confidence interval for Day 7 of coiled aneurysms (0 = none, 1 = mild, 2 = moderate, 3 = severe)
Bold emphasis refelects statistical significance

ISSN: 1742-2094