Fig. 5
From: Topographic distribution of inflammation factors in a healing aneurysm
Schematic representation of topographical patterns in a healing aneurysm. Overall, most factors (i.e., MMP2, MMP9, FGF) and cell types (CD163, CD3, HLA-DR) showed the highest accumulation in the neointima followed by the thrombus compartment but were neglectable in the aneurysm wall and in the adjacent vessel (A). Few factors (TNF-α, Il6) were equally distributed among the neointima and the thrombus (B). The accumulation of B cells (CD20) was higher in the thrombus than in the neointima and scarcely any B cells were found in the adjacent vessel wall (C). Lastly, endothelial cells () accumulate directly in the neointima, and their presence is associated with complete aneurysm healing