Fig. 1

miRNA-27a was downregulated in depression. a miRNA-27a mRNA expression in the serum of depressed patients (n = 24 per group). b miRNA-27a mRNA level in the serum or hippocampus of LPS mice (n = 10 per group). c miRNA-27a mRNA level in the serum or hippocampus of CDSD mice (n = 10 per group). Data are presented as mean ± SEM. *p < 0.05, **p < 0.01, compared to normal control group