Figure 2

Application of a low concentration of OLDA solution (0.2 μM) did not change mEPSC frequency in neurons, as recorded under control conditions (n = 25). The same OLDA application significantly increased mEPSC frequency in neurons recorded in spinal cord slices incubated with TNFα (60 nM; n = 10; ***P < 0.001). Values are given in percent of the corresponding mEPSC frequency before the OLDA application (100%).