Figure 1
From: Effects of mitochondrial dysfunction on the immunological properties of microglia
Mitochondrial toxins induce dose-dependent cell death of microglial cells. Microglial cells were treated with rotenone or 3-NP. After 24 hrs, cell viability (WST-1) and cell death (LDH) were measured as described in the Methods. Values are mean ± SEM for independent measurements. n = 8-18 wells (i.e., 4-9 separate experiments performed in duplicate); * = p < 0.05, *** = p < 0.001, significantly different from untreated cells (ANOVA followed by Dunnett's Multiple Comparison test).