Figure 3
From: Cellular injury and neuroinflammation in children with chronic intractable epilepsy
Triple immunofluorescence confocal images of neurons (green), microglia (blue) and astrocytes (red). Low magnification view of cortex (A) and white matter (B). (C--H) Higher magnification view showing close contact between microglia and astrocytes (C, D), neurons and microglia (E, F) and neurons and astrocytes (G, H). Activated microglia tend to co-localize with astrocytes (p = 0.054) (I). Activated microglia is inversely correlated with DNA fragmentation (p < 0.02, r = -0.38) (J). Bar = 20 μ m.