Figure 3

Vascular degeneration in the rabbits treated with 2.5 μg/kg Stx2. (A) In the infarction lesions in spinal cord gray matter, small vessels were damaged with extravascular exudates and occluded with fibrin-like (Th) and platelet (arrow) thrombi and with fragmented erythrocytes (arrow head). Some arteries and arterioles (B) in the spinal cord showed an endothelium with pycnotic nuclei and swollen cytoplasm as well as thickening of the vessel walls. (C) PTAH staining indicated that most of the thrombi and exudates or precipitates around the capillaries were formed with fibrin in both the spinal cord and brain parenchyma. (A) &(B): Elastica-Goldner staining. (Original magnification: 400×)