Figure 1
From: Human CNS cultures exposed to HIV-1 gp120 reproduce dendritic injuries of HIV-1-associated dementia
Seventy-two hour exposure to 1 nM gp120 causes observable cellular injury. Representative photomicrographs of control (a) and gp120 exposed (b) cultures. There is nuclear pyknosis, neuropil vacuolation and fewer visible cell processes in cultures exposed to gp120 for 72 hours. H&E, all bars = 25 μm.